日日干日日摸-日日干天天操-日日干天天草-日日干天天插-精品一区二区三区在线观看-精品一区二区三区在线观看l

熱門搜索: 硫酸角質素(KS)ELISA試劑盒(種屬:魚) 白介素6(IL6)ELISA試劑盒(種屬:魚) 魚白介素10(IL10)ELISA試劑盒發貨及時 斑馬魚白介素12BELISA試劑盒發貨及時 兔載脂蛋白B(apo-B)ELISA試劑盒發貨及時 兔孕酮(PROG)ELISA試劑盒發貨及時 兔羥脯氨酸(Hyp)ELISA試劑盒發貨及時 兔抗酒石酸酸性磷酸酶ELISA試劑盒發貨及時 兔晶體蛋白α(Cryα)ELISA試劑盒發貨及時 兔結締組織生長因子ELISA試劑盒發貨及時 兔基質金屬蛋白酶9ELISA試劑盒發貨及時 兔肺表面活性物質相ELISA試劑盒發貨及時 CD206分子ELISA試劑盒(種屬:小鼠) CC趨化因子受體6ELISA試劑盒(種屬:小鼠) 阻抑素(PHB)ELISA試劑盒(種屬:大鼠) 中性內肽酶;腦啡ELISA試劑盒(種屬:大鼠)

技術文章/ Technical Articles

您的位置:首頁  /  技術文章  /  引用大鼠ELISA科研檢測試劑盒的文獻

引用大鼠ELISA科研檢測試劑盒的文獻

更新時間:2023-09-19      瀏覽次數:1030

引用大鼠ELISA科研檢測試劑盒的文獻


文獻收集:

Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3- Mediated Pyroptosis

引用試劑盒:

種屬:大鼠

IL-1β (RJ15465), IL-18 (RJ15463),TNF-α (RJ16622), IL-6 (RJ15478), IL-10 (RJ15453),iNOS(RJ16565) , MDA (RJ15503), ROS(RJ15780) ,CAT(RJ15737),SOD(RJ16691) ,GSHPx(RJ25745) , LDH (RJ16172)

 

638272614877654132225.jpg

IF:7.675


Abstract: Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate NLRP3; thus, the ROS/NLRP3/pyroptosis axis plays a vital role in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI). Therefore, targeting the inhibition of the ROS/NLRP3/pyroptosis axis may be a promising therapeutic tactic for CIRI. Epimedium (EP) contains many active ingredients (ICA, ICS II, and ICT), which have a wide range of pharmacological activities. However, whether EP can protect against CIRI remains unknown. Thus, in this study, we designed to investigate the effect and possible underlying mechanism of EP on CIRI. The results showed that treatment with EP dramatically mitigated brain damage in rats following CIRI, which was achieved by suppressing mitochondrial oxidative stress and neuroinflammation. Furthermore, we identified the ROS/NLRP3/pyroptosis axis as a vital process and NLRP3 as a vital target in EP-mediated protection. Most interestingly, the main compounds of EP directly bonded with NLRP3, as reflected by molecular docking, which indicated that NLRP3 might be a promising therapeutic target for EP-elicited cerebral protection. In conclusion, our findings illustrate that ICS II protects against neuron loss and neuroinflammation after CIRI by inhibiting ROS/NLRP3-mediated pyroptosis.


image.png









微信掃一掃

郵箱:2450868877@qq.com

傳真:86-區號-傳真號碼

地址:上海市楊浦區鐵嶺路32號1519-10室

Copyright © 2025 上海仁捷生物科技有限公司版權所有   備案號:滬ICP備16052159號-1   總訪問量:270305   技術支持:化工儀器網

TEL:17302193538

掃碼加微信
主站蜘蛛池模板: 午夜高清视频在线观看| 小受被多男摁住—灌浓精| 美女把尿口扒开让男人桶| 国产精品日韩欧美一区二区三区| 久久伊人免费视频| 日本韩国欧美在线观看| 好男人视频社区精品免费| 亚洲视频国产视频| 日韩在线视频线视频免费网站| 中国一级片在线观看| 韩国三级日本三级香港三级黄| yy一级毛片免费视频| 啊公交车坐最后一排被c视频| 一区五十路在线中出| 成人免费漫画在线播放| 日本不卡一二三| 日本私人影院| 麻豆porno| 精品一区二区三区在线观看| 国产精品igao视频网| 老鸭窝在线视频观看| 妞干网免费视频| 欧美最猛黑人xxxx| 亚洲免费看片| 国产呦系列免费| 一本大道高清香蕉中文大在线| 成人理伦电影在线观看| 亚洲噜噜噜噜噜影院在线播放| 又大又硬又爽免费视频| 国产性片在线观看| 女人扒开裤子让男人捅| 老少交欧美另类| 精品国产国产综合精品| 日本免费电影一区| 久草这里只有精品| 中文字幕在线播放| 三级黄色在线观看| 成人性生交大片免费看| 停不了的爱在线观看高清| 青青热久免费精品视频精品 | 日韩欧美高清视频|